General Cell Based Assays
Eurofins Discoverx cAMP Hunter GPBAR1 Bioassay Kit, 2-Plate. (95-0049Y2-00139)
The cAMP Hunter CHO-K1 GPBAR1 Bioassay Kit provides a robust and highly sensitive functional, cell-based assay to measure drug potency and detect neutralizing antibodies. The bioassay kit contains all the materials needed to run the assay, including cryopreserved cells, detection reagents, cell plating reagent, positive control agonist, and assay plates. The ready-to-use cryopreserved cells have been manufactured to ensure long-term assay reproducibility, and faster implementation from characterization to QC lot release. This bioassay has been optimized for a 96-well format. The protocol can be optimized further for running the assay in a high-throughput 384-well format. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Eurofins Discoverx cAMP Hunter™ Human PPYR1 Gi Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human PPYR1 Gi Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure PPYR1 (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human F2RL1 β-Arrestin Cell-Based Assay Kit (HEK 293)
The PathHunter Human F2RL1 β-Arrestin Stable Cell Line Assay (HEK 293) β-Arrestin Cell Line contains a stable clonal cell line used to measure F2RL1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter eXpress CCRL2 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0333E2ACP1M)
The PathHunter CCRL2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CCL19) based activation of CCRL2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CCRL2 and EA-tagged β-Arrestin-2. Activation of CCRL2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Cayman Chemical THUNDERPhosphop38a MAPK 480
Sandwich TR-FRET immunoassay for semi-quantitative detection of Phospho-p38αβγ MAPK14/11/12 (T180/Y182) in cell lysates
Eurofins Discoverx cAMP Hunter™ Human TSHR(L) Gs Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human TSHR(L) Gs Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure TSHRL (GPCR) activity via increased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Cayman Chemical Hydroxyproline Assay Reagent 2, 14 mL
Hydroxyproline Assay Reagent 2 has been tested and formulated to work exclusively with Cayman’s Total Collagen/Hydroxyproline Assay Kit (Item No. 702440).
Eagle Biosciences Inc Ultra Sensitive Colorimetric Assay for Nitric Oxide Synthase
Ultra Sensitive Colorimetric Assay for Nitric Oxide Synthase
Eagle Biosciences Inc Nitric Oxide Synthase Non-Enzymatic Assay Kit
Nitric Oxide Synthase Non-Enzymatic Assay Kit
Revvity Health Sciences Inc HTRF Phospho-IR-β (Insulin Receptor Beta) (Tyr1150 /1151) Detection Kit, 500 Assay Points
HTRF Phospho-IR-β (Insulin Receptor Beta) (Tyr1150 /1151) Detection Kit, 500 Assay Points
Eurofins Discoverx PathHunter eXpress SSTR4 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0308E2CP2L)
The PathHunter SSTR4 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. somatostatin) based activation of SSTR4 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged SSTR4 and EA-tagged β-Arrestin-2. Activation of SSTR4 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter PDGFRb Bioassay Kit, 10-Plate. (93-0493Y3-00074)
The PathHunter PDGFRb Bioassay Kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This cell line enables assessment of ligand (e.g. PDGF-BB) based activation of PDGFRb receptors via detection of SH2 domain protein recruitment. The included cell line overexpresses ProLink-tagged PDGFRb target protein and EA-tagged SH2 domain protein. Upon activation of the receptor by its ligand or an agonist antibody, recruitment of SH2 domain protein to the phosphorylated receptor tail leads to production of EFC signal. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Eurofins Discoverx PathHunter eXpress OPRK1 U2OS β-Arrestin GPCR Assay, 2-Plate Kit. (93-0234E3CP5M)
The PathHunter OPRK1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. dynorphin A) based activation of OPRK1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged OPRK1 and EA-tagged β-Arrestin-2. Activation of OPRK1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress rGPR35 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0887E2RCP2M)
The PathHunter rGPR35 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. zaprinast) based activation of rGPR35 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged rGPR35 and EA-tagged β-Arrestin-2. Activation of rGPR35 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Rat version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
American Research Products Inc ELF5 Transcription Factor Activity Assay
ELF5 Transcription Factor Activity Assay